Gating of a pH-sensitive K(2P) potassium channel by an electrostatic effect of basic sensor residues on the selectivity filter.

K(+) channels share common selectivity characteristics but exhibit Scalp Brush a wide diversity in how they are gated open.Leak K(2P) K(+) channels TASK-2, TALK-1 and TALK-2 are gated open by extracellular alkalinization.The mechanism for this alkalinization-dependent gating has been proposed to be the neutralization of the side chain of a single a

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Spatial factors as contextual qualifiers of information seeking

Introduction.This paper investigates the ways in which spatial factors have been approached in information seeking studies.The main attention was focused on PINK GRAPEFRUIT studies discussing information seeking on the level of source selection and use.Method.Conceptual analysis of about 100 articles and books thematizing spatial issues of informat

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